منابع مشابه
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The effects of endopeptidase 24.11 inhibition on angiotensin-induced changes in plasma angiotensin II, aldosterone, and atrial natriuretic factor concentrations and blood pressure were assessed in normal volunteers. Two groups, each consisting of eight normal volunteers, received stepwise infusions of angiotensin II (2, 4, and 8 ng/kg per minute) on day 5 of dose administration with 25 mg every...
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Most ethical commentary on clinical research concerns studies involving patient-subjects. Several reasons may account for the relative neglect of ethical appraisal of research with healthy volunteers. Clinical research is often understood ethically within the context of, or in contrast to, the physician-patient relationship characteristic of medical care. In addition, research involving healthy...
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Second, the nature of volunteering is changing. Volunteers’ motivations and expectations have become more individualistic and ad-hoc and are less driven by long-term commitments. Moreover, contemporary volunteers increasingly expect their motivations and expectations to be met and are willing to leave the organizations if they do not perceive a good fit due to a mismatch between volunteer motiv...
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In connection with a study to determine whether man could be successfully immunized against bacillary dysentery it was necessary to determine the infective dose of dysentery bacilli by feeding living Shigella to human volunteers. The only previous information concerning the susceptibility of man to experimental infection is contained in a few published observations' 3 of accidental laboratory-i...
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The recent publication by Kelly et al. (1998) of their study on sucrose polyesters (SPE) raised concerns about the possible gastrointestinal (GI) and nutritional effects of olestra. These concerns were echoed in the popular press (‘Doubts raised over anti-obesity fat substitute’. The Times, 11 August 1998.). Olestra’s potential to cause GI and nutritional effects has been carefully reviewed by ...
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ژورنال
عنوان ژورنال: Medical Physics
سال: 2007
ISSN: 0094-2405
DOI: 10.1118/1.2728918